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What Is The Role Of Microglia In Autism?

What Is The Role Of Microglia In Autism?

Are you a parent or child who has got a lot of anxiety to know about things but fails in understanding it?

It is never easy to learn that someone whom you know and love has got a disorder in their developmental condition. This can leave you sad and confused.

Parenting a normal kid itself is a tedious task, keeping that in mind, parenting a child with autism has to be done more consciously with a lot of attention and care.

But one thing is certain that each child is unique.

Autism is not a condition which can be treated with medications and surgeries.

One of the major issue with autism is in most of the cases its cause remains unknown. As a lot of research has gone into it, researchers say that microglia has got a role in it.

Microglia - A Type Of Neuroglia

What Is Microglia?

It is a type of neuroglia(the cells present in your nervous system) present in brain and spinal cord. It is a neuronal support cell that occurs in the central nervous system of invertebrates and vertebrates that functions as an immune cell. They are the smallest cells in neuroglia which are typically oval-shaped.

In case if any infectious bodies are directly intruded the brain or cross the blood-brain barrier, then the microglial cells should react immediately to decrease inflammation and destroy the foreign bodies before they damage the sensitive neural tissue. Microglia have to recognize the foreign bodies, swallow them and act as antigen-presenting cells by activating T-cells.

What Is Autism?

Autism is a neurodevelopmental disorder that affects a person’s social, behavioral, and emotional patterns.

Autism is a spectrum condition in which the people find difficulty in interacting verbally and non-verbally with people and also fails in talking about their experiences and emotions. This can develop at a very young age and can remain lifelong if not treated properly.

Autism

How Is Microglia Related To Autism?

Neurons in the brain are the resident cells of the central nervous system. The neurons are connected to one another through the synapse. The synapse connection is the basis for the functioning of the nervous system. Initially, in the development stage synapses form in excess so this excess synapse is eliminated by microglia by engulfing the synapses that are less active. Any disruption in the synaptic connections can lead to a neurodevelopmental disorder like autism.

The causes of autism remain to be poorly understood.

Microglial cells can exhibit different functions during brain development including synaptogenesis and stem cell proliferation. Researches suggest that microglial activation or dysfunction can lead to dysfunction of neural development leading to autism.

In most of the cases, autism can be treated with proper guidance of a doctor and the coordination of parents and family members. Even though autistic children are unique they need not suffer their entire life by remaining in the same condition. There are therapies which can revert back the autistic child into normal life. The doctors at Ankura are here to help your loved ones.

About The Hospital: 

Ankura is a chain of  Children’s Hospital in Hyderabad. Set up in the year 2011 in KPHB, near Hitech Railway Station, the Ankura Hospitals family has today spread its wings to Secunderabad, Khammam, and Vijayawada.

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